Laugh lines, smile lines or more formally known as nasolabial folds, appear around the sides of the mouth vertically from the nose. These are caused by a combination of repetitive muscle movements and the different mechanisms of ageing. As we age, we lose structural proteins such as hyaluronic acid, and fat and skin descend in the face. These factors coupled with repeated muscle movements around the mouth, including smiling will create a pronounced fold.
There are also many external factors than can contribute to wrinkle formation: exposure to excess sun and smoking, use of medicines and drugs, weight loss, and daily life stress.
Perfectha is a range of hyaluronic acid (HA) dermal fillers designed to treat different signs of ageing throughout the face.
Perfectha DERM should be used for moderate smile lines
Perfectha DEEP is indicated for deep smile lines
*Low adverse event rate: 0.026% from October 2014 to December 2018
1Talarico S. et al. Evaluation of the safety and efficacy of a new fi ller with hyaluronic acid for the treatment of nasolabial folds and lip contour; Surg. Cosmet. Dermatol.2010;2(2):83-67- Park KY1, Kim HK, Kim
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